Cross-sectional investigation on rickets of 150 preschoolers and analysis of the relation between 25(OH)D3 level and X-ray
- QU Jian-ping1, YANG Shu-fen1, YANG Tao2, REN Li-hong1, YAO Li1, TIAN Zhi-liang1, WANG Wei1, ZHANG Xue-lian1
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Abstract
【Objective】 To investigate the prevalence of rickets for the preschool children and the relation between 25(OH)D3 level and X-ray in rachitic patients. 【Methods】 On January 2010, physical examination, medical history collection, blood test and X ray film of left wrist were did in 150 preschoolers who were randomly selected among 5 kindergartens and 2 preschool classes in the city of Suihua, then the data were analysed. 【Results】 52 preschoolers were suffering from rickets among the 150 preschoolers. The prevalence of rickets was 34.6%, it was not related with gender and age. The 25-(OH)D3 level in the rickets group with X-ray change was lower than that in the control group, and there were significant differences. 【Conclusions】 Rickets is still existed in preschoolers, but all of them are mild; The survey of 150 preschool children show that preschoolers in Suihua generally have vitamin D deficiency and shortages; The lower 25(OH)D3 level, the more likely X-ray changes are happen.
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References
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[2] 于清,韩秀玲.学龄前小儿佝偻病患病情况分析[J].中国初级卫生保健, 2009,3(1):4-6.
[3] 刘清华.矿区学龄前儿童佝偻病发病状况调查分析[J].基层医学论坛,2010,14(5):5-7.
[4] 常立文.营养性维生素D缺乏性佝偻病[M]∥薛辛东.儿科学.2版.北京:人民卫生出版社,2010:83-90.
[5] Graff M, Thacher TD, Fischer PR, et al. Calcium absorption in Nigerian children with rickets[J]. Am J Clin Nutr,2004,80:1415-1421.
[6] Frank RG. 25-hydrixyvitamin D: functional outcomes in infants and young children[J].Am J Clin Nutr,2008,88(S):529-533.
[7] Hathcock JN, Shao A,Vieth R, et al. Risk assessment for vitamin D[J].Am J Clin Nutr,2007,85(1):6-18.
[8] Holick MF. Vitamin D deficiency[J].N Engl J Med,2007,357(3):266-281.
[9] Dawodu A, Agarwal M, Sankarankutty M, el at. Higher prevalence of vitamin D deficiency in mothers of rachitic than nonrachitic children[J]. Pediatrics,2005,147(1):109-111.
[10] 马贤才,王加义.儿童骨健康[M].北京:人民卫生出版社,2007:172-183.
[11] 赵亚茹,马学梅.2008年《婴幼儿及少年儿童维生素D缺乏和佝偻病的预防》解读分析[J].中国实用儿科杂志,2009,24(3):174-176.
[12] Carol LW, Frank RG. The Section on breastfeeding and committee on Nutrition. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents[J]. Pediatrics,2008,122(5):1142-1152.
