Objective To analyze the difference on the overall developmental outcomes measured by Development Screening Test (DST) in children with abnormal and normal results of general movements (GMs), in order to explore the correlation between GMs assessment mild neurologic dysfunction. Methods Participants were recorded with GMs assessment results during writhing and fidgety movement period from 2009 to 2017.And the developmental quotient (DQ) and mental index (MI) were assessed by DST at 9,12 and 24 months old. Results Single factor analysis showed that there was no significant differences on DQ and MI results between children with normal and abnormal GMs assessment results among 9,12 and 24-month-old infants.After adjusting confounding factors, abnormal results of GMs fidgety movement indicated high risk of abnormal developmental outcomes(9 months old:OR=3.075,95%CI:1.013-9.331;12 months old:OR=3.638,95%CI:1.552-8.527;24 months old:OR=2.750,95%CI:1.213-6.242).The sensibility of GMs assessment to predict later outcome was low(8.82%~18.60%), while the specificity was high(>95%). Conclusion GMs assessment has limitation to predict later development outcome of infants, and can not replace other development assessments.
Key words
premature infants /
general movements /
neurocognitive development
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References
[1] 杨红.全身运动(GMs)评估在高危儿运动发育随访中的应用研究[D]. 上海:复旦大学,2009.
[2] Hadders-Algra M.Neural substrate and clinical significance of general movements:an update[J].Dev Med Child Neurol,2018,60(1):39-46.
[3] 尹欢欢,杨红.全身运动评估在早产儿及小婴儿脑发育评估中的应用[J].中国实用儿科杂志,2017,32(11):816-820.
[4] Spittle AJ, Spencersmith MM, Cheong JL, et al.General movements in very preterm children and neurodevelopment at 2 and 4 years[J]. Pediatrics,2013,132(2):452-458.
[5] Olsen JE, Allinson LG, Doyle LW, et al.Preterm and term-equivalent age general movements and 1-year neurodevelopmental outcomes for infants born before 30 weeks′ gestation[J].Dev Med Child Neurol,2018,60(1):47-53.
[6] Salavati S, Einspieler C, Vagelli G, et al.The association between the early motor repertoire and language development in term children born after normal pregnancy[J].Early Hum Dev,2017,111:30-35.
[7] Cunha M, Correa F, Cadete A, et al.Predictive value of cerebellar growth and general movements assessments for neurodevelopment of very preterm infants at 18-24 months′ corrected age[J].Rev Neurol,2017,64:63-69.