基于CiteSpace的孤独症谱系障碍-肠脑轴近十年国际知识网络图谱可视化分析

doi:10.11852/zgetbjzz2024-0438

中国儿童保健杂志 ›› 2025, Vol. 33 ›› Issue (1): 103-111.DOI: 10.11852/zgetbjzz2024-0438

基于CiteSpace的孤独症谱系障碍-肠脑轴近十年国际知识网络图谱可视化分析

田艳萍, 李威, 李庆红, 吴嘉娜, 赖燕媚, 姜雪, 吕智海

深圳市龙岗区妇幼保健院(汕头大学医学院龙岗妇幼临床学院)儿童康复科, 广东深圳 518100

收稿日期:2024-04-17 修回日期:2024-06-17 发布日期:2025-01-16 出版日期:2025-01-10
通讯作者: 吕智海,E-mail:13613602038@163.com
作者简介:田艳萍(1995—),女,初级康复治疗师,硕士学位,主要研究方向为孤独症谱系障碍的肠道菌群研究。
基金资助:
深圳市龙岗区科技创新专项资金医疗卫生技术攻关项目(LGKCYLWS2023006);龙岗区医疗卫生科技计划项目[LGWJ2022-(42)];龙岗区医疗卫生科技计划项目[LGWJ2021-(55)];龙岗区医疗卫生科技计划项目[LGWJ2021-(63)];深圳市龙岗区妇幼保健院科研启动资金项目(Y2024010)

Visualization analysis of international knowledge network mapping of the autismspectrum disorder-gut-brain axis in the last decade based on CiteSpace

TIAN Yanping, LI Wei, LI Qinghong, WU Jiana, LAI Yanmei, JIANG Xue, LYU Zhihai

Department of Children's Rehabilitation, Longgang District Maternity & Child Healthcare Hospital of Shenzhen City (Longgang Maternity and Child Institute of Shantou University Medical College), Shenzhen, Guangdong 518100, China

Received:2024-04-17 Revised:2024-06-17 Online:2025-01-10 Published:2025-01-16
Contact: LYU Zhihai, E-mail:13613602038@163.com

摘要/Abstract

摘要： 目的运用CiteSpace可视化图谱分析软件概述国际孤独症谱系障碍(ASD)-肠脑轴领域的现有研究结构,尝试识别并预测此领域的研究热点及热点演变趋势。方法以Web of Science数据库为文献来源,以2013—2023年间发表的ASD-肠脑轴相关文献记录为研究对象,利用CiteSpace软件对相关文献记录进行可视化分析,分别绘制并解读国家、机构、作者、共被引文献和关键词等方面的相关知识图谱。结果 2013—2023年外文年均发文量为52.3篇。合作发文高产国家为美国、中国及意大利。合作发文高产机构为爱尔兰科克大学、美国加州大学、美国哈佛大学。合作发文高产团队以Dinan TG团队为代表。热点关键词为肠道菌群、肠易激综合征、短链脂肪酸、丁酸钠、嗜黏蛋白阿克曼氏菌。预测肠道菌群通过肠-脑轴对ASD的神经发育调节的机制及针对ASD的肠道微生物组靶向疗法研究将是未来一段时间内的研究热点。结论 ASD-肠脑轴这一研究领域虽起步较晚,但发展较为迅速。本文指出了可合作的作者、机构并预测了研究热点,以期为此领域相关课题的研究提供参考。

关键词: 孤独症谱系障碍, 肠-脑轴, 微生物-肠-脑轴, 知识网络图谱, CiteSpace, Web of Science, 可视化分析

Abstract: Objective To use CiteSpace visualization mapping software to outline the existing research structure in the international field of autism spectrum disorder(ASD)-gut-brain axis, so as to identify and predict research hotspots and their evolving trends in this area. Methods Using the Web of Science database as the source of literature, documents related to ASD-gut-brain axis published between 2013 and 2023 were recorded. CiteSpace software was used to conduct visual analysis of the related literature records, and to draw and interpret the related knowledge map in terms of countries, institutions, authors, co-citations and keywords. Results The average annual number of foreign publications from 2013 to 2023 was 52.3. The most productive collaborating countries were the United States, China, and Italy. The most productive collaborating institutions included University College Cork in Ireland, the University of California in the USA, and Harvard University in the USA. The most productive research team was represented by the group led by Dinan TG. Hotspot keywords included gut microbiota, irritable bowel syndrome, short-chain fatty acids, sodium butyrate, and akkermansia muciniphila. It was predicted that the mechanism of neurodevelopmental regulation of ASD by gut flora through the gut-brain axis and the study of gut microbiome-targeted therapies for ASD will be the research hotspots in the near future. Conclusions The research field of autism-gut-brain axis, although started late, is developing more rapidly. This paper points out potential collaborative authors and institutions and predicts research hotspots, aiming to provide a reference for related studies in this field.

Key words: autism spectrum disorder, gut-brain axis, microbiota-gut-brain axis, scientific knowledge atlas, CiteSpace, Web of Science, visual analysis

中图分类号:

G353
R749.94

田艳萍, 李威, 李庆红, 吴嘉娜, 赖燕媚, 姜雪, 吕智海. 基于CiteSpace的孤独症谱系障碍-肠脑轴近十年国际知识网络图谱可视化分析[J]. 中国儿童保健杂志, 2025, 33(1): 103-111.

TIAN Yanping, LI Wei, LI Qinghong, WU Jiana, LAI Yanmei, JIANG Xue, LYU Zhihai. Visualization analysis of international knowledge network mapping of the autismspectrum disorder-gut-brain axis in the last decade based on CiteSpace[J]. Chinese Journal of Child Health Care, 2025, 33(1): 103-111.

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基于CiteSpace的孤独症谱系障碍-肠脑轴近十年国际知识网络图谱可视化分析

Visualization analysis of international knowledge network mapping of the autismspectrum disorder-gut-brain axis in the last decade based on CiteSpace

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