维生素A与新生儿呼吸系统疾病关系的研究进展

doi:10.11852/zgetbjzz2020-1454

摘要/Abstract

摘要： 维生素A是一种脂溶性维生素,它参与广泛的生理过程,如胚胎发育,视觉发育以及细胞分化和增殖。视黄酸(RA)是维生素A主要的活性形式,它调节着多个器官的发育过程。在早期肺发育形成过程中需要足够的维生素A。慢性维生素A缺乏与肺的组织病理学变化有关,这种变化会破坏正常的肺生理,从而导致严重呼吸系统疾病。本文主要对维生素A与新生儿呼吸系统疾病关系做一总结,为临床治疗提供一定的指导。

关键词: 维生素A, 肺发育, 先天性膈疝, 支气管肺发育不良, 新生儿呼吸窘迫综合征

Abstract: Vitamin A is a fat-soluble vitamin that participates in a wide range of physiological processes, such as embryonic development, visual development, cell differentiation and proliferation.Retinoic acid (RA) is the main active form of vitamin A, which regulates the development of multiple organs.Sufficient vitamin A is needed during early lung development.Chronic vitamin A deficiency is related to the histopathological changes of the lungs, which can disrupt normal lung physiology, leading to severe respiratory diseases.This review mainly summarizes the relationship between vitamin A and neonatal respiratory diseases, thus to provide guidance for clinical treatment.

Key words: Vitamin A, lung development, congenital diaphragmatic hernia, bronchopulmonary dysplasia, newborn respiratory distress syndrome

中图分类号:

R725.6

李倩倩, 姜泓. 维生素A与新生儿呼吸系统疾病关系的研究进展[J]. 中国儿童保健杂志, 2021, 29(5): 523-526.

LI Qian-qian, JIANG Hong. Research progress on the association between vitamin A and neonatal respiratory diseases[J]. Chinese Journal of Child Health Care, 2021, 29(5): 523-526.

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