Abstract: Objective To identify the status of serum vitamin A,D,E levels of infants and young children and to provide reference for clinical diagnosis and treatment. Methods Totally 67 healthy infants and young children were recruited for the study from January to March in 2013.Serum vitamin A,25-hydroxy vitamin D[25(OH)D],vitamin E were determined.Basic situation,feeding methods,physical and other aspects of the information were collected. Results Altogether 67 children,included 40 boys and 27 girls.The mean serum vitamin A was (0.23±0.07) mg/L,the rate of lack was 34.33%.Stratified analysis showed serum levels of different age had differences (F=5.866,P=0.001).Serum vitamin A deficiency rate gradually decreased with the month age increase.The 0~4 months of age group was the lowest with (0.17±0.04) mg/L,the lack rate was high as 68.75%.There were also differences in serum vitamin levels of different feeding methods (F=2.838,P=0.045),serum levels of exclusively breastfed infants was minimum with (0.18±0.03) mg/L,the lack rate was 60.00%.Serum 25(OH)D level was (102.26±90.54) nmol/L,the lack rate was 13.33%.There were differences between the different feeding methods (F=2.951,P=0.038).Serum levels of exclusively breastfed infants was low with (96.93±20.42) nmol/L,the higher rate of lack was 33.34%.Serum vitamin E level was (10.09±2.76) mg/L,rate of insufficient was only 13.4%,and there were no children.Vitamin E was better overall nutritional status. Conclusions Children's nutrition of vitamin A and 25(OH)D situations were not optimistic.The attention of the government should be improved to timely applying intervention to prevent vitamin deficiency for high-risk groups.

Key words: vitamin A, 25 hydroxyl vitamin D, vitamin E, the level of serum

摘要： 目的 了解婴幼儿血清维生素A、D、E水平状况,为临床诊治工作提供参考。方法 以2013年1-3月在首都儿科研究所附属儿童医院保健门诊67名要求健康体检儿童作为研究对象,采用高效液相色谱检测血清维生素A、25羟维生素D[25(OH)D]、维生素E水平,收集其基本情况、喂养方式、体格等方面信息。结果 67名儿童中,男40例,女27例。维生素A水平为(0.23±0.07)mg/L,缺乏率34.3%,不同月龄段血清水平差异有统计学意义(F=5.866,P=0.001),随月龄增加血清维生素A缺乏率逐渐减少,0~4个月组最低[(0.17±0.04)mg/L],缺乏率高达68.8%;不同喂养方式血清维生素A水平差异有统计学意义(F=2.838,P=0.045),纯母乳喂养组血清水平偏低[(0.18±0.03)mg/L],缺乏率为60.0%。血清25(OH)D水平为(102.26±90.54)nmol/L,缺乏率为13.3%;不同喂养方式水平差异有统计学意义(F=2.951,P=0.038),纯母乳喂养婴儿仍偏低[(96.93±20.42)nmol/L],缺乏率较高为33.3%。血清维生素E水平为(10.09±2.76)mg/L,不足率仅为13.4%,未发现缺乏儿童,维生素E营养状况良好。结论 婴幼儿维生素A、D营养状况不容乐观,应针对高危人群及时施加干预以预防维生素缺乏症的发生。

关键词: 维生素A, 25羟维生素D, 维生素E, 血清水平