Case-control study on risk factors of childhood autism.

XIAN Dan-xia; JIN Yu; XIE Xiao-ying; LIN Mei-ying; ZHANG Ling; LI Chao-juan; HONG Rong.

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Chinese Journal of Child Health Care ›› 2014, Vol. 22 ›› Issue (1) : 24-27.

Case-control study on risk factors of childhood autism.

XIAN Dan-xia¹, JIN Yu¹, XIE Xiao-ying², LIN Mei-ying³, ZHANG Ling¹, LI Chao-juan^{1, 4}, HONG Rong^{1, 5}.

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Abstract

Objective To find out risk factors associated with children with autism and to offer the basis for autistic prevention work. Methods There were 165 patients children with autism and 320 patientscontrol group of children in the case-control study.Questionnaires were used to make up by ourselves to collect maternal risk factors, family and other general information, and then used Chi-square test to analyze the two sets of children's differences in risk factors. Results The proportion of higher maternal age (≥35 years old) and father introverted, higher maternal induced abortion, maternal depression and passive smoking during the pregnant time in autism group were higher than those in the normal group (P<0.05), and logistic analysis showed that higher maternal age, father introverted, higher maternal induced abortion, maternal depression and passive smoking during the pregnant time were the risk factors to autism in children. Conclusion Mother aged (≥35 years old), a history of induced abortion, passive smoking and depression in gestation period and father introverted are risk factors to autism.

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autism / risk factors / children

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XIAN Dan-xia, JIN Yu, XIE Xiao-ying, LIN Mei-ying, ZHANG Ling, LI Chao-juan, HONG Rong.. Case-control study on risk factors of childhood autism.[J]. Chinese Journal of Child Health Care. 2014, 22(1): 24-27

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