Objective To understand the intervention effect of health education on preschool children's health,and to explore a suitable model for preschool children. Methods Using self-prepared health education materials and self-designed toys to carry out movements.Questionnaires were applied to learn the changes in knowledge,attitude and behavior before and after health education. Results After the education,there were significant improvement in the health related knowledge,attitude and behavior,especially in the prevention of vitamin A deficiency,parents' correct answer rate was 19.34%~80.66%,then increased to 66.85%~92.27%; and children correct answer rate was 14.36%~46.96%,then increased to 67.96%~80.11%,the knowledge awareness and good behavior rate increased significantly (P<0.01). Conclusion The comprehensive health intervention model combined with children and parents can improve the adherence of children and parents for health education,and effectively improve the knowledge,attitude and behavior of children and parents.