Abstract: Objective To explore the relationship between children with attention deficit hyperactivity disorder (ADHD) and their blood lead,zinc and ferrum levels. Method Blood lead,zinc and ferrum levels of 70 ADHD children and 60 healthy controls were determined by atomic absorption spectrometry. Results The blood zinc and ferrum levels [(74.39±10.71)μmol/L,(8.52±0.58)mmol/L] were lower in ADHD children,than those in health controls [(80.60±9.07)μmol/L,(8.76±0.51)mmol/L,t=3.538 or 2.536,P<0.01 or <0.05].The blood lead level [(57.3±20.9)μg/L] was higher in ADHD children than that in health controls [(45.9±17.4)μg/L,t=3.357,P<0.01]. Conclusion Blood lead is high and zinc and ferrum is deficient in some ADHD children,which should be determined routinely and retrieved as soon as possible.

Key words: attention deficit hyperactivity disorder, blood lead, blood zinc, blood ferrum, children

摘要： 目的 探讨儿童注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)和血铅(Pb)、锌(Zn)、铁(Fe)水平的关系。方法 选择70例ADHD患儿和60例正常对照儿童,采用原子吸收光谱法测定血铅、锌、铁含量。 结果 ADHD组儿童锌(74.39±10.71)μmol/L,铁(8.52±0.58)mmol/L,明显低于健康对照组儿童(80.60±9.07)μmol/L,(8.76±0.51)mmol/L,差异有统计学意义(t=3.538,2.536,P<0.01或<0.05)。ADHD组儿童血铅(57.3±20.9)μg/L,明显高于健康对照组儿童(45.9±17.4)μg/L,差异有统计学意义(t=3.357,P<0.01)。 结论 部分ADHD患儿存在高血铅、锌、铁缺乏,在诊治时应常规检测并及早纠正。

关键词: 注意缺陷多动障碍, 铅, 锌, 铁, 儿童