【Objective】 In order to know the distribution of TSH and incidence of congintal hypothroid newborns in Guangxi provinces,and study the cutoff for newborn screen. 【Method】 The dates of newborn screen centre of Guangxi Zhuang Autoumous Region were analyzed,which was about 270 590 neonatals,and calculated the TSH cutoff by percent and ROC curve,then,analyzed the complexion of sufferers by different cutoff. 【Results】 The distribution of newborn screen was deflection,P50 was 1.89 mU/L,P99 was 8.13 mU/L,combined with ROC curve,the cutoff of our lab was 8.1 mU/L. 【Conclusion】 Different cutoff effect the consequences of newborn screen.To establish establish the suitable cutoff based on lab is important.
Key words
congenital hypothyroidism /
newborn screen /
cutoff /
thyrotropic-stimulating hormone
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