Study of mismatch negativity in newborn infants

GAO Yan; HONG Qi; LUO Xiao-xing; XU Hui-lian; YAO Xiao-fang; JIN Yan; JIANG Tao-tao; ZHUO Xiu-hui; LU Guang-jin

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Chinese Journal of Child Health Care ›› 2011, Vol. 19 ›› Issue (5) : 415-418.

Study of mismatch negativity in newborn infants

GAO Yan, HONG Qi, LUO Xiao-xing, XU Hui-lian, YAO Xiao-fang, JIN Yan, JIANG Tao-tao, ZHUO Xiu-hui, LU Guang-jin

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Abstract

【Objective】 To explore the mismatch negativity(MMN) of healthy newborn infants. 【Methods】 Auditory event-related potentials of 56 neonates ages ranged from 2 to 3 days were elicited with the oddball paradigm. Stimuli consisted of 1 000 Hz tones with 80% probability as standard and 2 000 Hz with 20% probability as deviant. 【Results】 MMN were obtained from 35 infants of all subjects. The distribution of MMN was mainly in the frontal area. The latencies at F3, F4 and Fz were (234±50), (248±51) and (239±45) ms. There was no significant difference between the right and left hemisphere in the mean amplitude of 150 to 450 ms time-window. 【Conclusion】 MMN can be elicited in healthy newborn infants.

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GAO Yan, HONG Qi, LUO Xiao-xing, XU Hui-lian, YAO Xiao-fang, JIN Yan, JIANG Tao-tao, ZHUO Xiu-hui, LU Guang-jin. Study of mismatch negativity in newborn infants[J]. Chinese Journal of Child Health Care. 2011, 19(5): 415-418

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