Changes of blood trace elements and serum BALP in children with idiopathic short stature
- ZHANG Jian, LI Jun-xin, ZHANG Lu
Author information
+
History
+
Abstract
【Objective】 To measure the levels of blood trace elements and serum bone alkaline phosphatase(BALP) in children with idiopathic short stature and investigate their influences on the children's height. 【Method】 The levels of Blood Ca, Zn, Fe Cu, Mg, Pb and serum BALP were measured and analyzed in both idiopathic short stature group and control group. 【Result】 Both blood Ca, Zn levels were significantly lower than those of control group, but blood Pb and serum BALP levels were apparently higher than those of control group. 【Conclusions】 Pb exposure can influence children's height and that may be one factor of ISS as well as the short of blood Ca and Zn. In addition, the level of serum BALP in children with idiopathic short stature can be used as a curative effect symbol.
Key words
idiopathic short stature / serum Pb / trace element / bone alkaline phosphatase
{{custom_sec.title}}
{{custom_sec.title}}
References
[1] 楚冬梅,孙桂香. 生长激素受体基因单核苷酸多态性与特发性矮小的相关性[J]. 医学综述, 2007, 13 (11) : 833-835.
[2] 陈克,陈均亚,叶祎.铅对儿童甲状腺功能影响的研究[J].中国儿童保健杂,2009,17 (1): 87-88.
[3] 陈克,叶祎,留佩宁,等.特发性矮小儿童身高与血铅的相关性[J].实用儿科临床杂志,2008,23(8):602-603.
[4] 黄丽敏.矮身材儿童血铅镉锌钙铁铜镁水平分析[J].四川医学,2009,30(7):1084-1086.
[5] 张红艳.微量元素与儿童佝偻病[J].中国儿童保健杂志,2005,13(3):241-242.
[6] 陈华琼.矮身材儿童血清锌、铁、铜、钙、镁含量分析[J].中国儿童保健杂志, 2006, 14 (3):290-292.
[7] 王敬群.特发性身材矮小儿童血清骨碱性磷酸酶和骨钙素的测定及临床意义[J].中国妇幼保健,2008,23(21):2987-2988.
[8] 王映峰,郭建贵.佝偻病患儿骨碱性磷酸酶检测及临床分析[J].包头医学院学报,2008,25(1):74-75.
[2] 陈克,陈均亚,叶祎.铅对儿童甲状腺功能影响的研究[J].中国儿童保健杂,2009,17 (1): 87-88.
[3] 陈克,叶祎,留佩宁,等.特发性矮小儿童身高与血铅的相关性[J].实用儿科临床杂志,2008,23(8):602-603.
[4] 黄丽敏.矮身材儿童血铅镉锌钙铁铜镁水平分析[J].四川医学,2009,30(7):1084-1086.
[5] 张红艳.微量元素与儿童佝偻病[J].中国儿童保健杂志,2005,13(3):241-242.
[6] 陈华琼.矮身材儿童血清锌、铁、铜、钙、镁含量分析[J].中国儿童保健杂志, 2006, 14 (3):290-292.
[7] 王敬群.特发性身材矮小儿童血清骨碱性磷酸酶和骨钙素的测定及临床意义[J].中国妇幼保健,2008,23(21):2987-2988.
[8] 王映峰,郭建贵.佝偻病患儿骨碱性磷酸酶检测及临床分析[J].包头医学院学报,2008,25(1):74-75.
