【Objective】 To establish a quality assurance system to ensure that children's systematic health care performs its seven functions correctly, which contains testing, evaluating, guiding and so on, and provides standard, convenient and allround health care services to children. 【Methods】 To investigate the process of systematic health care according to relevant policy rules, the components of quality system for systematic health care was analyzed. Study was designed from four aspects: running subject, process approach, supporting conditions and evaluation. 【Results】 The quality assurance system for children's health care management was established, which was based on "testing-evaluating-guiding" integration and some corresponding supporting elements. The system covered all the critical quality control points and solved the difficulties in quality control and execution standard of systematic health care. 【Conclusions】 Establishing and operating a quality assurance system is an effective quality control method for children's health care management.