【Objective】 To explore the effect of hypertension disorder complicating pregnancy (HDCP) on neuropsychological development of their 2~5 years old offspring. 【Methods】 Using 1∶1 matched case-control study method, chosen 27 offspring in HDCP group and control group. The intelligence was evaluated utilizing 0~6 years infant neuropsychological development scale. The relevant informations were collected, including living environments and lifestyle behaviors. 【Results】 The offspring with HDCP mother were lower than the normal children in the gestational duration days, birth weight and birth length (P<0.05). The language and socialization dimension of neuropsychological development and developmental quotient (DQ) were lower in offspring of HDCP than those of control in 2~5 years old (P<0.05). On the living environment, there was negative correlation between socialization and passive smoking (P＜0.05), but positive correlation between socialization and number of inhabitant (P＜0.05). On the lifestyle behaviors, there was a positive correlation between outdoor activities time, liking to communicate with other children and socialization, DQ (P＜0.05), but a negative correlation between the time for watching TV/computer and socialization and DQ (P＜0.05). 【Conclusions】 The living environment and the lifestyle behaviors of HDCP can affect the neuropsychological development. Early intervention is necessary for the neuropsychological development in offspring of HDCP.
Key words
hypertension disorder complicating pregnancy /
offspring /
neuropsychological development
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