Role of telomeres in the relationship between early life adverse environments and metabolic diseases

HE Yuhua, XIONG Fei

Chinese Journal of Child Health Care ›› 2024, Vol. 32 ›› Issue (8) : 886-890.

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Chinese Journal of Child Health Care ›› 2024, Vol. 32 ›› Issue (8) : 886-890. DOI: 10.11852/zgetbjzz2024-0143
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Role of telomeres in the relationship between early life adverse environments and metabolic diseases

  • HE Yuhua1, XIONG Fei1,2
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Abstract

Numerous epidemiological and animal experimental studies have shown that in addition to lifestyle and genetic inheritance, exposure to adverse factors in early life may increase the risk of metabolic diseases in adult offspring by affecting fetal telomere length. However, the mechanism by which early exposure to adverse factors increases the risk of metabolic diseases is still unclear. Exploring telomere biological information may provide new avenues for predicting adverse environmental exposure in early life and postnatal health issues.

Key words

telomeres / telomerase / intrauterine factors / metabolic diseases

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HE Yuhua, XIONG Fei. Role of telomeres in the relationship between early life adverse environments and metabolic diseases[J]. Chinese Journal of Child Health Care. 2024, 32(8): 886-890 https://doi.org/10.11852/zgetbjzz2024-0143

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