Therapeutic effect of low frequency repetitive transcranial magnetic stimulation combined with task oriented training on lower extremity gross motor function and gait function of children with spastic hemiplegic cerebral palsy

ZHANG Qiu; LI Weiping; YU Jihua; DU Xinping; LING Yunqi; XU Fangyuan

doi:10.11852/zgetbjzz2023-0103

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Chinese Journal of Child Health Care ›› 2023, Vol. 31 ›› Issue (11) : 1248-1253. DOI: 10.11852/zgetbjzz2023-0103

Therapeutic effect of low frequency repetitive transcranial magnetic stimulation combined with task oriented training on lower extremity gross motor function and gait function of children with spastic hemiplegic cerebral palsy

ZHANG Qiu, LI Weiping, YU Jihua, DU Xinping, LING Yunqi, XU Fangyuan

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Abstract

Objective To analyze the effect of low frequency repetitive transcranial magnetic stimulation (rTMS) combined with task oriented training (TOT) on lower extremity gross motor and gait function of children with spastic hemiplegic cerebral palsy, in order to provide new ideas for improving the motor function of spastic hemiplegic cerebral palsy. Methods From August 2021 to September 2022, 75 children aged 3 - 6 years with spastic hemiplegic cerebral palsy were selected into this study from the Outpatient and Inpatient Departments of Rehabilitation Medicine in the Affiliated Southwest Medical University, and were randomly divided into routine group (n=25), TOT group (n=25) and rTMS+TOT group (n=25). Children in the three groups all received conventional rehabilitation. Additionally, children in TOT group received TOT, children in rTMS+TOT group received TOT combined with low frequency rTMS. Children in the three groups were assessed with Modified Ashworth Scale (MAS), D and E domains of Gross Motor Function Measure-88(GMFM-88) and footprint analysis before and after treatment. Results After 6-week intervention, scores of the above indicators in the three groups improved significantly than those before intervention (P<0.05). Intergroup comparison showed that performance of MAS (H=20.995), D and E domains of GMFM-88 (F=12.348, 19.428), turnover step length (F=2.137), step width (F=12.160) and 1 minute walk test (1MWT) distance assessment (F=8.705) were significantly better than those in TOT group and routine group (P<0.05). Conclusion Low frequency rTMS combined with TOT could decrease the gastrocnemius muscle tone and improve the lower extremity gross motor and gait function in children with spastic hemiplegic cerebral palsy, and the effect is better than TOT alone.

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low frequency repetitive transcranial magnetic stimulation / task-oriented training / spastic hemiplegic cerebral palsy / lower extremity gross motor / gait function

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ZHANG Qiu, LI Weiping, YU Jihua, DU Xinping, LING Yunqi, XU Fangyuan. Therapeutic effect of low frequency repetitive transcranial magnetic stimulation combined with task oriented training on lower extremity gross motor function and gait function of children with spastic hemiplegic cerebral palsy[J]. Chinese Journal of Child Health Care. 2023, 31(11): 1248-1253 https://doi.org/10.11852/zgetbjzz2023-0103

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