Correlation of maternal cholesterol and oxysterols during pregnancy with cognitive development in the offspring

YU Huan-ling

doi:10.11852/zgetbjzz2021-0285

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Chinese Journal of Child Health Care ›› 2021, Vol. 29 ›› Issue (4) : 349-351. DOI: 10.11852/zgetbjzz2021-0285

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Correlation of maternal cholesterol and oxysterols during pregnancy with cognitive development in the offspring

YU Huan-ling

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Abstract

Cholesterol, the essential material for brain development, is transported continuously from mothers to fetus during the gestation stage to meet the need of embryonic and fetal development. Oxysterols are oxygenated derivatives of cholesterol or its sterol precursors, and may be closely related to brain function. Population studies have found that the serum/plasma cholesterol levels of pregnant women are correlated with the risk of developing attention-deficit hyperactivity disorder and autism spectrum disorders in offspring, but the research evidence needs to be improved.

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cholesterol / oxysterol / cognitive development / brain development

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YU Huan-ling. Correlation of maternal cholesterol and oxysterols during pregnancy with cognitive development in the offspring[J]. Chinese Journal of Child Health Care. 2021, 29(4): 349-351 https://doi.org/10.11852/zgetbjzz2021-0285

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