Research advances on the relationship between melatonin and sleep problems in children with autism spectrum disorder

WANG Jing-qiu; WANG Cheng-ju; HU Bin

doi:10.11852/zgetbjzz2021-0215

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Chinese Journal of Child Health Care ›› 2022, Vol. 30 ›› Issue (6) : 651-654. DOI: 10.11852/zgetbjzz2021-0215

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Research advances on the relationship between melatonin and sleep problems in children with autism spectrum disorder

WANG Jing-qiu, WANG Cheng-ju, HU Bin

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Abstract

Autism spectrum disorder(ASD) is a group of neurodevelopmental disorders,often accompanied by circadian rhythm disorders and sleep problems. Sleep problems may not only aggravate some of the core symptoms of ASD children,but also affect the effect of rehabilitation training. The clinical manifestations of sleep problems in ASD children are various,but the exact mechanism is not clear. Studies have found that it is closely related to abnormal melatonin secretion and metabolism,and melatonin treatment is effective and safe. This paper mainly reviews the sleep problems of ASD children and the research progress related to melatonin in order to provide basis for improving sleep quality of ASD children and formulating effective intervention programs.

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autism spectrum disorder / sleep problem / melatonin / children

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WANG Jing-qiu, WANG Cheng-ju, HU Bin. Research advances on the relationship between melatonin and sleep problems in children with autism spectrum disorder[J]. Chinese Journal of Child Health Care. 2022, 30(6): 651-654 https://doi.org/10.11852/zgetbjzz2021-0215

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