Objective To analyze the bacterial composition and clinical significance of sputum in children with severe pneumonia,in order to provide scientific evidence for clinical treatment. Methods A total of 1 136 children in Pediatric Intensive Care Unit of Children′s Hospital of Kaifeng were selected from May 2013 to January 2018.The drug resistance characteristics of the isolates were analyzed. Results A total of 921 pathogens were detected in 667 sputum specimens,mainly Gram-negative bacteria(708 strains). Bacterial distribution was not significantly different in different age groups.Klebsiella pneumoniae and Pseudomonas aeruginosa mainly existed in spring,summer and autumn.Staphylococcus aureus was mainly in winter.Klebsiella pneumoniae and Pseudomonas aeruginosa showed high resistance to AMK,GEN,CIP(87.86%,83.24%,81.50%) as well as CAZ,CPD and FOX(77.18%,77.18%,66.44%),respectively.And Staphylococcus aureus was primarily resistant to IPM,COT,FOX and ERY(82.68%,73.23%,70.08%,70.08%). Conclusion The pathogens in children with severe pneumonia are characterized by a clear seasonal distribution,and treatment should be based on past experience and drug resistance.
Key words
severe pneumonia /
bacteria /
sputum /
children
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