Analysis of quality of life of phenylketonuria children with early dietary treatment

QIU Ting; XU Yin; WANG Li-zhen; ZHANG Heng; GUO Bing-bing; JIANG Xin-ye

doi:10.11852/zgetbjzz2018-26-07-29

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Chinese Journal of Child Health Care ›› 2018, Vol. 26 ›› Issue (7) : 796-798. DOI: 10.11852/zgetbjzz2018-26-07-29

Analysis of quality of life of phenylketonuria children with early dietary treatment

QIU Ting, XU Yin, WANG Li-zhen, ZHANG Heng, GUO Bing-bing, JIANG Xin-ye

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Abstract

Objective To analyze the quality of life of 2 to 4-year-old children with phenylketonuria(PKU) and its correlation with phenylalanine (Phe) concentration,in order to provide guidance for clinical treatment. Methods Totally 15 children diagnosed with PKU born from June 2011 to June 2015 were investigated by The Quality of Life Inventory,and the score of Quality of Life Inventory was compared between PKU children and normal children.And the correlation of quality of life with phenylalanine level was analyzed. Results In emotional function dimension,score of item on feeling less sad and depressed in 2 to 4-year-old children with early treatment was significantly lower than that in healthy children(P＜0.01),but the differences on other items of quality of life between the two groups were not significant.Besides,there was no significant correlation between phenylalanine level and quality of life(P＞0.05). Conclusion Early dietary treatment is crucial to improve quality of life of PKU children,and normal phenylalanine level of PKU children may guarantee the good quality of life.

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phenylketonuria / quality of life / phenylalanine level

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QIU Ting, XU Yin, WANG Li-zhen, ZHANG Heng, GUO Bing-bing, JIANG Xin-ye. Analysis of quality of life of phenylketonuria children with early dietary treatment[J]. Chinese Journal of Child Health Care. 2018, 26(7): 796-798 https://doi.org/10.11852/zgetbjzz2018-26-07-29

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