Objective To explore the association between home environment and infant language delay,in order to provide reference for promoting the language development in early childhood.Methods A total of 112 infants diagnosed with language delay were enrolled as case group in Shanghai Children′s Hospital from November 2017 to August 2018,and 127 normal infants matched with gender and age who took physical examination in the same hospital at the same period were as control group.Chinese Home Nurture Environment Questionnaire and Infant Language Delay Questionnaire were used to conduct this survey. Results The education level of parents in children with language delay was significantly lower than that of normal children.Likewise,the developmental quotients (DQs) of motor,object,language and social abilities in children with language delay were lower (P＜0.01).Besides,the normal children had better home environment than language delay children(Z=-2.884,P=0.004),and the differences were statistically significant,especially on emotional warmth & home environment atmosphere,social adaptation & relfcane,language & cognitive information environment (Z=-2.032,-3.974,-4.835,P＜0.05 or 0<0.01).After controlling confounding factors,home nurture environment was found to be a significantly influential factor for language development of children (P＜0.01).The language developmental quotient was relevant to home environment(r=0.480,P＜0.01),and if children′s home environment scores increased 1 point,the language developmental quotient (DQ) increased by 0.45 on average. Conclusion Home nurture environment is one of important influential factors to children′s language development,so it is suggested to give more opportunities for children participating in cognitive activities,thereby improving the quality of parent-child interaction.