Dynamic monitoring of platelet during bronchopulmonary dysplasia in premature infants

FU Pei-pei; XIE Meng; CUI Hong

doi:10.11852/zgetbjzz2018-0774

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Chinese Journal of Child Health Care ›› 2019, Vol. 27 ›› Issue (6) : 656-658. DOI: 10.11852/zgetbjzz2018-0774

Dynamic monitoring of platelet during bronchopulmonary dysplasia in premature infants

FU Pei-pei, XIE Meng, CUI Hong

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Abstract

Objective To investigate the relationship between platelet and preterm infant with bronchopulmonary dysplasia(BPD). Methods Data of premature infants with gestational age less than 32 weeks,and living more than 28 days in Beijing Friendship Hospital were retrospectively analyzed from January 2013 to April 2017.Children were classified into case group and control group according to the BPD diagnosis.The mean values of four indexes of platelet during hospitalization,including platelet count (PLT),platelet width (PDW),mean platelet volume (MPV) and platelet count (PCT),and those at ≤7 days,7＜-14 days and 14＜-21 days were analyzed. Results Totally 87 preterm infants met the inclusion criteria,and 79 cases were included in this study finally.There were 30 cases in BPD group (case group) and 49 cases in non-BPD group (control group).The gestational age and birth weight in case group were significantly lower than those in control group(P＜0.001).The levels of PLT and PCT in case group were significantly decreased compared with control group (P=0.008,0.003).And the level of MPV in case group significantly lower than that in control group in 7 days after birth (P＜0.001). Conclusion The formation and development of pulmonary micro vessels play an important role in the development of BPD,and platelets may be the key role in this process of BPD.

Key words

bronchopulmonary dysplasia / pathogenesis / pathogenic mechanism / premature infants

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FU Pei-pei, XIE Meng, CUI Hong. Dynamic monitoring of platelet during bronchopulmonary dysplasia in premature infants[J]. Chinese Journal of Child Health Care. 2019, 27(6): 656-658 https://doi.org/10.11852/zgetbjzz2018-0774

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