川崎病患儿疾病恢复早期身体活动水平评估

doi:10.11852/zgetbjzz2024-1172

中国儿童保健杂志 ›› 2025, Vol. 33 ›› Issue (8): 888-892.DOI: 10.11852/zgetbjzz2024-1172

川崎病患儿疾病恢复早期身体活动水平评估

王聪颖^1*, 张梦楠^2*, 成童², 张明明¹, 王宏茂¹, 张霆³, 关宏岩^2,3, 李晓惠¹

1.首都儿科研究所附属儿童医院心内科,北京 100020;
2.首都儿科研究所婴幼儿照护服务研究指导中心/儿童保健中心;
3.首都儿科研究所儿童发育营养组学北京市重点实验室

收稿日期:2024-10-14 修回日期:2025-03-05 发布日期:2025-08-04 出版日期:2025-08-10
通讯作者: 张霆,E-mail: zhangtingcv@126.com;关宏岩,E-mail: hongyanguan@126.com;李晓惠,E-mail: lxhmaggie@pumc.edu.cn
作者简介:王聪颖(1992—),女,博士研究生,主要研究方向为川崎病发病机制。张梦楠(1996—),女,硕士研究生,主要研究方向为学龄前儿童身体活动与健康。^*共同第一作者。
基金资助:
首都儿科研究所2023基础与临床结合项目(JHYJ-2023-01)

Assessment of physical activity level in children with Kawasaki disease during early recovery stage

WANG Congying^1*, ZHANG Mengnan^2*, CHENG Tong², ZHANG Mingming¹, WANG Hongmao¹, ZHANG Ting³, GUAN Hongyan^2,3, LI Xiaohui¹

1. Department of Cardiology, Children's Hospital of Capital Institute of Pediatrics, Beijing 100020,China;
2. Nurturing Care Research and Guidance Center/Children's Health Center, Capital Institute of Pediatrics-Peking University Teaching Hospital

Received:2024-10-14 Revised:2025-03-05 Online:2025-08-10 Published:2025-08-04
Contact: ZHANG Ting, E-mail: zhangtingcv@126.com;GUAN Hongyan, E-mail: hongyanguan@126.com;LI Xiaohui, E-mail: lxhmaggie@pumc.edu.cn

摘要/Abstract

摘要： 目的评估学龄前期川崎病患儿疾病早期的身体活动(PA)水平,为制定个体化运动处方提供依据。方法以2023年12月—2024年3月在首都儿科研究所附属儿童医院住院的川崎病患儿为川崎病组,按1∶3以性别、年龄匹配的健康儿童为对照组。在川崎病患儿病程1月时采用学龄前儿童园外运动行为问卷(P-PAQ)调查患儿近1周的身体活动水平。通过电子病历系统收集川崎病患儿的临床资料,包括性别、年龄、身高、体重、治疗方案、实验室指标(血常规、C-反应蛋白)及冠状动脉超声结果。结果本研究共纳入112名儿童,其中川崎病患儿28名、健康对照组儿童84名。川崎病患儿病程1月时园外总活动时间为99.36(56.79,130.18)min/d,户外活动时间为12.86 (10.71,14.29)min/d,中高强度活动时间为26.25(7.50, 53.32)min/d。与健康对照组相比,川崎病患儿园外总活动时间、户外活动时间、中高强度活动时间均显著减少,差异有统计学意义(Z=5.491、5.072、3.726, P＜0.01)。所有川崎病患儿追踪至病程1月随访时,无冠状动脉并发症及心血管不良事件发生。结论学龄前川崎病不伴冠状动脉并发症患儿疾病早期身体活动处于低水平,积极探索疾病恢复期基于循证医学证据的个体化运动处方具有重要临床指导意义。

关键词: 身体活动, 川崎病, 运动处方, 学龄前儿童

Abstract: Objective To assess the physical activity (PA) levels in preschool children with Kawasaki disease (KD) during the early stages of the illness,in order to provide reference for making individualized exercise prescriptions. Methods Children hospitalized at the Children's Hospital of Capital Institute of Pediatrics between December 2023 and March 2024 were selected as the KD group. Healthy children matched by gender and age in a 1∶3 ratio served as the control group. The Preschooler Physical Activity Questionnaire (P-PAQ) was used to evaluate the PA levels of the KD group one month after the onset of the disease, focusing on their physical activity over the past week. The clinical data of KD patients were collected through the electronic medical system, including gender, age, height, weight, treatment, laboratory indicators (blood routine, C-reactive protein) and ultrasound results of coronary arteries. Results A total of 112 children were included in the study, comprising 28 KD patients and 84 healthy controls. One month after the onset of KD, the total out-of-school activity time was 99.36 (56.79, 130.18) minutes per day, the outdoor activity time was 12.86 (10.71, 14.29) minutes per day, and the moderate-to-vigorous physical activity (MVPA) time was 26.25 (7.50, 53.32) minutes per day. Compared to the healthy control group, the KD group showed significantly reduced total out-of-school activity time, outdoor activity time, and MVPA time (Z=5.491, 5.072, 3.726, P<0.01). All KD patients were followed up one month after the onset of the disease, and no coronary artery complications or adverse cardiovascular events were observed. Conclusions Preschool children with KD without coronary artery complications exhibit low levels of physical activity during the early stage of the disease. Actively exploring individualized exercise prescriptions based on evidence-based medicine during the recovery phase holds significant clinical importance.

Key words: physical activity, Kawasaki disease, exercise prescription, preschool children

中图分类号:

R179

王聪颖, 张梦楠, 成童, 张明明, 王宏茂, 张霆, 关宏岩, 李晓惠. 川崎病患儿疾病恢复早期身体活动水平评估[J]. 中国儿童保健杂志, 2025, 33(8): 888-892.

WANG Congying, ZHANG Mengnan, CHENG Tong, ZHANG Mingming, WANG Hongmao, ZHANG Ting, GUAN Hongyan, LI Xiaohui. Assessment of physical activity level in children with Kawasaki disease during early recovery stage[J]. Chinese Journal of Child Health Care, 2025, 33(8): 888-892.

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川崎病患儿疾病恢复早期身体活动水平评估

Assessment of physical activity level in children with Kawasaki disease during early recovery stage

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