关键词: 灌注指数, 平均动脉压, 动脉血乳酸, 新生儿危重病例评分

Abstract: Objective To explore the effectiveness of perfusion index (PI) in monitoring neonatal circulation,so as to find out a sensitive and easy way for circulation monitoring of neonates. Methods Newborns admitted to the Neonatal Intensive Care Unit (NICU) of Xinxiang Central Hospital from October 2018 to July 2019 were selected,and the neonatal critical illness score (NCIS) was performed after admission. The score >90 was non-critical,the score between 70 and 90 was critical,and the score<70 was extremely critical. Fifty-four children who were in critical or extremely critical condition and underwent invasive blood pressure monitoring with the consent and signature of their families were selected and included in the study. Mean arterial pressure (MAP) was recorded,and PI,blood lactic acid,heart rate,SPO₂ and left ventricular ejection fraction (EF) were monitored simultaneously. Results 1)There was a moderate positive correlation between PI and MAP (r=0.724,P=0.01) and a moderate negative correlation between PI and blood lactic acid (r=-0.688,P<0.01). The correlation between PI and heart rate,SPO₂,left ventricular ejection fraction (EF) was not significant. ROC curve showed that when the cut-off point of PI was 0.67,the sensitivity and specificity of PI for predicting MAP were 87.8% and 76.9%,with the AUC of 0.872 (P<0.01). When the cut-off point of PI was 1.35,the sensitivity and specificity of PI for predicting blood lactic acid were 100.0% and 77.3%,with the AUC of 0.931(P<0.01). Conclusions PI is a sensitive index for monitoring neonatal circulation.

Key words: perfusion index, mean arterial pressure, arterial blood lactic acid, neonatal critical illness score