目的 研究影响早产儿发生的环境危险因素,为采取针对的防治措施提供依据。方法 对93例早产儿行1∶1配对病例对照研究,进行生活工作及心理环境危险因素的调查,收集的资料进行单因素及多因素条件Logistic 回归分析。结果 单因素及多因素条件Logistic 回归分析显示:情绪紧张、室内装修史、被动吸烟、住房周围空气污染、人际关系紧张及烹调油烟可能是早产儿发生的危险因素。结论 针对早产儿发生的危险因素,应做好孕期保健,以降低早产儿的发生率。
Abstract
Objective To study the environmental risk factors of preterm infants,so as to offer basis for making effective preventive and control measures. Methods A 1∶1 match case-control method was used to choose 93 preterm birth cases and 93 control cases,an epidemiological investigation was carried out about life and work and psychological environmental risk factors of preterm birth,and at the same time,univariate and multivariate conditional Logistic regression model were used to screen risk factors. Results The results of univariate and multivariate conditional Logistic regression analysis showed that emotional tension,interior decoration,passive smoking,the air pollution around housing,interpersonal relation tension and cooking fumes might be the risk factors of preterm delivery. Conclusion Prenatal care should be taken targeting to risk factors of premature delivery to improve outcome of premature delivery.
关键词
环境 /
危险因素 /
早产儿
Key words
environment /
risk factors /
premature
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 姚荣英,庄颖,陶芳标.早产儿的骨发育问题及其影响因素[J].中国儿童保健杂志,2007,15(1):62-64.
[2] 张美云,王雷,徐丽珍,等.早产的环境危险因素病例对照研究[J].环境与健康杂志,2012,29(9):802-805.
[3] Choi SM,Yoo SD,Lee BM.Toxico logical characteristics of endocrine-disrupting chemicals:Developmental toxicity,carcinogenicity,and mutagenicity[J].J Toxicol Environ Health B Crit Rev,2004,7(1):1-24.
[4] 李敏,杨秀群,陈淑明,等.脐带血铅含量与新生儿出生体重关系的探讨[J].中国儿童保健杂志,2000,8(3):165-166.
[5] Nishijo M,Nakagawa H,Honda R,et al.Effeets of maternal exposure to cadmium on pregnancy outeome and breast milk[J].Occup Environ Med,2002,59(6):394-397.
[6] 徐丽珍,薛小平,张燕,等.太原市孕期空气污染暴露对早产的影响[J].环境与健康杂志,2008,25(4):298-301.
[7] Leem J,Kaplan H,Shim BM,et al.Exposures to air pollutants during pregnancy and preterm delivery[J].Environ Health Perspect,2006,114:905-910.
[8] Iiguez C,Ballester F,Amorós R,et al.Active and passive smoking during pregnancy and ultrasound measures of fetal growth in a cohort of pregnant women[J].J Epidemiol Community Health,2011.[Epub ahead of print].
[9] Antonopoulos C,Sergentanis T,Papadopoulou C,et al.Maternal smoking during pregnancy and childhood lymphoma:A meta-analysis[J].Int J Cancer,2011.[Epub ahead of print].
[10] 汤春珠,范建霞.孕妇吸烟对妊娠结局及子代健康影响的研究现状[J].中华围产医学杂志,2009,12(5):385-387.
[11] 曹亚南,张燕,刘登.极低频电磁场对小鼠雌性生殖和子代生长发育的影响[J].中华劳动卫生职业病杂志,2006,24(8):468-470.
[12] Marcus M,McChesney R,Golden A,et al.Video display terminals and miscarriage[J].J Am Med Women Assoc,2000,55(2):84-88.
[13] Ohnishi Y,Mizuno F,Sato T,et al.Effects of power frequency alternationg magnetic fields on reproduction and prenatal development of mice[J].J Toxicol Sci,2002,27:131-138.
[14] Orr ST,Reiter JP,Blazer DG,et al.Maternal prenatal pregnancy-related anxietyand spontaneous preterm birth in baltimore[J].Maryland Psychosom Med,2007,69(6):566-570.
基金
济宁市科技发展计划项目(2013jnwk67)