[1] Ranke MB.Towards a consensus on the definition of idiopathic short stature[J].Horm Res,1996,45(S2):64-66.
[2] Cohen P,Rogol AD,Deal CL,et al.Consensus statement on the diagnosis and treatment of children with idiopathic short stature:a summary of the growth hormone research society,the lawson wilkins pediatric endocrine society,and the European society for paediatric endocrinology workshop[J].The Journal of Clinical Endocrinology & Metabolism,2008,93(11):4210-4217.
[3] Ranke MB.Towards a consensus on the definition of idiopathic short stature,summary[J].Horm Res,1996,45 (S2):64-66.
[4] Wit JM,Clayton PE,Rogol AD,et al.Idiopathic short stature:definition, epidemiology,and diagnostic evaluation[J].Growth Horm IGF Res,2008,18(2):89-110.
[5] Weedon MN,Lettre G,Freathy RM,et al.A commonvariant of HMGA2 is associated with adult and childhood height in the general population[J].Nat.Genet,2007,39:1245-1250.
[6] Gudbjartsson DF,Walters GB,Thorleifsson G,et al.Many sequence variants affecting diversity of adult human height[J].Nat Genet,2008,40(5):609-615.
[7] Yang J,Benyamin B,McEvoy BP,et al.Common SNPs explain a large proportion of the heritability for human height[J].Nat Genet,2010,42(7):565-569.
[8] Wit JM.Definition and subcategorization of idiopathic short stature:between consensus and controversy[J].Horm Res Paediatr,2011,76(S3):3-6.
[9] Weedon MN,Frayling TM.Reaching new heights:insights into the genetics of human stature[J].Trends Genet,2008,24(12):595-603.
[10] De Bellis A,Colao A,Tirelli G,et al.Autoimmunity as a possible cause of growth hormone deficiency[J].J Endocrinol Invest,2008,31(12):1132-1134.
[11] Trovato L,Prodam F,Genoni G,et al.Involvement of genes related to inflammation and cell cycle in Idiopathic Short Stature[J].Pituitary,2012 Mar 1.[Epub ahead of print]
[12] Munns CF,Glass IA,Lanagan SF,et al.Familial growth and skeletal features associated with SHOX haploinsufficiency[J].J Pediatr Endocrinol Metab,2003,16:987-996.
[13] Rappold G,Blum WF,Shavrikova EP,et al.Genotypes and phenotypes in children with short stature:clinical indicators of SHOX haploinsufficiency[J].J Med Genet,2007,44:306-313.
[14] Cetin I,Foidart JM,Miozzo M,et al.Fetal growth restriction:a workshop report[J].Placenta,2004,25(8-9):753-757.
[15] Albertsson-Wikland K,Karlberg J.Natural growth in children born SGA with and without catch up growth[J].Horm Res,2003,59 (S1):129-135.
[16] Loche S,Bizzarri C,Maghnie M,et al.Results of early reevaluation of growth hormone secretion in short children with apparent growth hormone deficiency[J].J Pediatr,2002,140:445-449.
[17] Attie KM,Carlsson LM,Rundle AC,et al.Evidence for partial growth hormone insensitivity among patients with idiopathic short stature:the national cooperative growth study[J].J Pediatr,1995,127:244-250.
[18] Savage MO,Burren CP,Rosenfeld RG.The continuum of growth hormone-IGF-I axis defects causing short stature:diagnostic and therapeutic challenges[J].Clin Endocrinol (Oxf),2010,72:721-728. [19] Wit JM.Definition and subcategorization of idiopathic short stature:between consensus and controversy[J].Horm Res Paediatr,2011,76 (S3):3-6.
[20] www.accessdata.fda.gov/drugsatfda_docs/label/2011/020280s071lbl.pdf.
[21] 中华医学会儿科学分会内分泌遗传代谢学组.矮身材儿童诊治指南[J].中华儿科杂志,2008,46(6):428-430.
[22] Bryant J,Baxter L,Cave CB,et al.Recombinant growth hormone for idiopathic short stature in children and adolescents[J].Cochrane Database Syst Rev,2007,3:CD004440.
[23] Wit JM,Rekers-Mombarg LT,Cutler GB,et al.Growth hormone (GH) treatment to final height in children with idiopathic short stature:evidence for a dose effect[J].J Pediatr,2005,146:45-53.
[24] Leschek EW,Rose SR,Yanovski JA,et al.Effect of growth hormone treatment on adult height in peripubertal children with idiopathic short stature:a randomized,double-blind,placebo-controlled trial[J].J Clin Endocrinol Metab,2004,89:3140-3148.
[25] Quigley CA,Gill AM,Crowe BJ,et al.Safety of growth hormone treatment in pediatric patients with idiopathic short stature[J].J Clin Endocrinol Metab,2005,90(9):5188-5196.
[26] Writing Group for the SEARCH for Diabetes in Youth Study Group,Dabelea D,Bell RA,et al.Incidence of diabetes in youth in the United States[J].JAMA,2007,297(24):2716-2724.
[27] Kemp SF,Kuntze J,Attie KM,et al.Efficacy and safety results of long-term growth hormone treatment of idiopathic short stature[J].J Clin Endocrinol Metab,2005,90(9):5247-5253.
[28] Pedicelli S,Peschiaroli E,Violi E,et al.Controversies in the definition and treatment of idiopathic short stature (ISS)[J].J Clin Res Pediatr Endocrinol,2009,1(3):105-115.
[29] 王德芬.促线性生长:芳香化酶抑制剂[J].国际内分泌代谢杂志,2008,28(3):149-152.
[30] Chernausek SD,Backeljauw PF,Frane J,et al.GH insensitivity syndrome collaborative group long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity[J].J Clin Endocrinol Metab,2007,92:902-910.
[31] Ambler GR,Fairchild J,Wilkinson DJ.Debate:Idiopathic short stature should be treated with growth hormone[J].J Paediatr Child Health,2012 May 15.doi:10.1111/j.1440-1754.2012.02465.x.