维生素D补充剂应用现状及影响因素研究进展
- 毕晓娜 综述,衣明纪 审校
作者信息
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文章历史
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摘要
维生素D(vitamin D, VitD)是人体不可缺少的一种脂溶性维生素。近年来VitD功能的研究发现VitD缺乏除与骨骼肌肉系统疾病有关外,还与心血管疾病、代谢性疾病、免疫系统疾病以及心理疾病等多系统疾病的发生相关。研究还显示全球VitD缺乏的患病率仍很高,严重影响儿童的健康。因此合理补充VitD对预防VitD缺乏、促进儿童健康是非常重要的,但是目前VitD补充剂的应用情况不理想,并且影响因素复杂。美国及欧洲多项研究显示VitD补充剂的应用率较低,我国目前这方面的流行学资料较少。
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参考文献
[1] Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences [J]. Am J Clin Nutr,2008,87(S):1080-1086.
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[4] 中华医学会儿科学分会儿童保健学组,《中华儿科杂志》编辑委员会.儿童微量营养素缺乏防治建议[J].中华儿科杂志,2010,48(7):502-509.
[5] Piccino MF, Dwyer JT, Radimer KL, et al. Dietary supplement use among infants, children, and adolescents in the United States, 1999-2002 [J]. Arch Pediatr Adolesc Med, 2007,161 (10):978-985.
[6] Perrine CG, Sharma AJ, Jefferds MED, et al. Adherence to vitamin D recommendations among US infants[J]. Pediatrics,2010,125(4): 627-632.
[7] Yetley EA. Assessing the vitamin D status of the US population [J]. Am J Clin Nutr, 2008, 88(2S):558-564.
[8] Gordon CM, Feldman HA, Sinclair L, et al. Prevalence of vitamin D deficiency among healthy infants and toddlers [J]. Arch Pediatr Adolesc Med, 2008,162(6):505-512.
[9] Taylor JA, Geyer LJ, Feldman KW. Use of supplemental vitamin D among infants breastfed for prolonged periods [J]. Pediatrics,2010,125(1):105-111.
[10] Dodd KW, Guenther PM, Freedman LS, et al. Statistical methods for estimating usual intake of nutrients and foods: a review of the theory [J]. J Am Diet Assoc,2006,106(10):1640-1650.
[11] 黄晓凤,梁和平,甄国新,等.北京市顺义区农村4～12月龄婴幼儿营养素补充剂现状调查[J].职业与健康,2010,26(11):1247-1249.
[12] Holick MF. High prevalence of vitamin D inadequacy and implications for health [J]. Mayo Clin Proc,2006,81(3):353-373.
[13] Lee JH, O'Keefe JH, Bell D, et al. Vitamin D deficiency: an important, common, and easily treatable cardiovascular risk factor[J]. JACC,2008,52(24):1949-1956.
[14] Bikle D. Nonclassic actions of vitamin D[J]. J Clin Endocrinol Metab,2009,94(1):26-34.
[15] Ginde AA, Liu MC, Camargo CA. Demographic differences and trends of vitamin D insufficiency in the US population, 1988—2004[J]. Arch Intern Med, 2009,169(6):626-632.
[16] Webb AR. Who, what, where and when influences on cutaneous vitamin D synthesis [J]. Prog Biophys Mol Biol,2006,92(1):17-25.
[17] American Academy of Pediatrics, Committee on environmental health. ultraviolet light: a hazard to children [J]. Pediatrics,1999,104(2):328-333.
[18] Holvik K, Meyer HE, Haug E, et al. Prevalence and predictors of vitamin D deficiency in five immigrant groups living in Oslo, Norway: the Oslo Immigrant Health Study[J]. Eur J Clin Nutr,2005,59(1):57-63.
[19] Garland CF, Garland FC, Gorham ED, et al. The role of vitamin D in cancer prevention[J]. Am J Public Health,2006,96(2):252-261.
[20] Hollis BW, Wagner CL. Assessment of dietary vitamin D requirements during pregnancy and lactation [J]. Am J Clin Nutr,2004,79(5):717-726.
[21] Sherman EM, Svec RV. Barriers to vitamin D supplementation among military physicians [J]. Mil Med,2009,173(3):302-307.
[22] Shaikh U, Alpert PT. Practices of vitamin D recommendation in Las Vegas, Nevada [J]. J Hum Lact, 2004,20(1):56-61.
[23] Davenport ML, Uckun A, Calikoglu AS. Pediatrician patterns of prescribing vitamin supplementation for infants: do they contribute to rickets？[J]. Pediatrics,2004,113(1):179-180.
[2] Wagner CL, Greet FR. The section on breastfeeding and committee on nutrition.Prevention of rickets and vitamin D deficiency in infants, children, and adolescents [J]. Pediatrics, 2008,122(5):1142-1152.
[3] 《中华儿科杂志》编辑委员会,中华医学会儿科学分会儿童保健学组,全国佝偻病防治科研协作组.维生素D缺乏性佝偻病防治建议[J].中华儿科杂志,2008,46(3):190-191.
[4] 中华医学会儿科学分会儿童保健学组,《中华儿科杂志》编辑委员会.儿童微量营养素缺乏防治建议[J].中华儿科杂志,2010,48(7):502-509.
[5] Piccino MF, Dwyer JT, Radimer KL, et al. Dietary supplement use among infants, children, and adolescents in the United States, 1999-2002 [J]. Arch Pediatr Adolesc Med, 2007,161 (10):978-985.
[6] Perrine CG, Sharma AJ, Jefferds MED, et al. Adherence to vitamin D recommendations among US infants[J]. Pediatrics,2010,125(4): 627-632.
[7] Yetley EA. Assessing the vitamin D status of the US population [J]. Am J Clin Nutr, 2008, 88(2S):558-564.
[8] Gordon CM, Feldman HA, Sinclair L, et al. Prevalence of vitamin D deficiency among healthy infants and toddlers [J]. Arch Pediatr Adolesc Med, 2008,162(6):505-512.
[9] Taylor JA, Geyer LJ, Feldman KW. Use of supplemental vitamin D among infants breastfed for prolonged periods [J]. Pediatrics,2010,125(1):105-111.
[10] Dodd KW, Guenther PM, Freedman LS, et al. Statistical methods for estimating usual intake of nutrients and foods: a review of the theory [J]. J Am Diet Assoc,2006,106(10):1640-1650.
[11] 黄晓凤,梁和平,甄国新,等.北京市顺义区农村4～12月龄婴幼儿营养素补充剂现状调查[J].职业与健康,2010,26(11):1247-1249.
[12] Holick MF. High prevalence of vitamin D inadequacy and implications for health [J]. Mayo Clin Proc,2006,81(3):353-373.
[13] Lee JH, O'Keefe JH, Bell D, et al. Vitamin D deficiency: an important, common, and easily treatable cardiovascular risk factor[J]. JACC,2008,52(24):1949-1956.
[14] Bikle D. Nonclassic actions of vitamin D[J]. J Clin Endocrinol Metab,2009,94(1):26-34.
[15] Ginde AA, Liu MC, Camargo CA. Demographic differences and trends of vitamin D insufficiency in the US population, 1988—2004[J]. Arch Intern Med, 2009,169(6):626-632.
[16] Webb AR. Who, what, where and when influences on cutaneous vitamin D synthesis [J]. Prog Biophys Mol Biol,2006,92(1):17-25.
[17] American Academy of Pediatrics, Committee on environmental health. ultraviolet light: a hazard to children [J]. Pediatrics,1999,104(2):328-333.
[18] Holvik K, Meyer HE, Haug E, et al. Prevalence and predictors of vitamin D deficiency in five immigrant groups living in Oslo, Norway: the Oslo Immigrant Health Study[J]. Eur J Clin Nutr,2005,59(1):57-63.
[19] Garland CF, Garland FC, Gorham ED, et al. The role of vitamin D in cancer prevention[J]. Am J Public Health,2006,96(2):252-261.
[20] Hollis BW, Wagner CL. Assessment of dietary vitamin D requirements during pregnancy and lactation [J]. Am J Clin Nutr,2004,79(5):717-726.
[21] Sherman EM, Svec RV. Barriers to vitamin D supplementation among military physicians [J]. Mil Med,2009,173(3):302-307.
[22] Shaikh U, Alpert PT. Practices of vitamin D recommendation in Las Vegas, Nevada [J]. J Hum Lact, 2004,20(1):56-61.
[23] Davenport ML, Uckun A, Calikoglu AS. Pediatrician patterns of prescribing vitamin supplementation for infants: do they contribute to rickets？[J]. Pediatrics,2004,113(1):179-180.
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