【目的】 通过对新生儿血浆蛋白测定结果分析,探讨生后早期血浆蛋白质量对新生儿营养状况评估价值。 【方法】 选取120例新生儿为研究对象,分以下四组:早产小于胎龄儿组(small for gestational age, SGA)30例,早产适于胎龄儿(appropriate for gestational age, AGA)组30例,足月小于胎龄儿组30例,足月适于胎龄儿组30例。所有研究对象生后24 h 内静脉采血测定血浆蛋白进行比较分析。 【结果】 1)SGA组血浆前白蛋白质量(serum protein mass/prealbumin, SPM/PA)显著低于AGA组;2)早产儿AGA组白蛋白(albumin, ALB)低于足月儿AGA组;3)早产儿组前白蛋白(prealbumin, PA)及SPM/PA均低于足月儿组。上述差异均有统计学意义(P<0.05)。 【结论】 1)新生儿早期SPM/PA是评价新生儿营养状况的重要指标;2)SPM/PA还可作为评定胎龄,区分适于胎龄儿和小于胎龄儿的有效指标。

【Objective】 To explore the value of neonatal serum protein mass in assessment of neonatal nutrition. 【Methods】 120 studied neonates were divided into four groups: premature neonates in small for gestational age(SGA), premature neonates in appropriate for gestational age(AGA), full-term neonates in SGA and full-term neonates in AGA including 30 neonates, respectively. All the neonates were collected the venous serum to detect the serum protein within 24 hours after delivery. The results were compared and analyzed to sum up their characteristics. 【Results】 1)The serum protein mass of prealbumin (SPM/PA) in SGA were lower than those in AGA significantly. 2)The albumin (ALB) of premature neonates in AGA were lower than those of full-term neonates in AGA significantly. 3)The concentration of prealbumin (PA) and SPM/PA in premature neonates was significantly lower than that in full-term neonates(P<0.05, respectively). 【Conclusions】 1)The neonatal SPM/PA is not only important but also sensitive to reflect neonatal nutrition status and evaluate the effect of support therapy. 2)Furthermore, as an effective indicator, SPM/PA can also distinguish SGA from AGA neonates.